The injection helps increase sex drive, reduce obesity
The new treatment of male obesity with testosterone injections is as effective as gastric bypass surgery, with fewer complications.
Research lasting more than 11 years suggests testosterone injections could be a new treatment for obese men, reducing body mass by up to 20%.
The study data, presented at the European and International Congress on Obesity, took place online in September. The researchers gathered data since 2004, with 471 men with impaired sexual function, have low testosterone and obesity hormones, from urological clinics in Germany.
About 58% of the men received testosterone injections every three months during the study period, the remainder without any treatment, acting as controls. The average age of the participants was 61.5.
Medical staff records all injections at clinic, ensuring all participants receive consistent treatment. No participants dropped out of the study.
As a result, those who injected testosterone lost an average of 23 kg (equivalent to 20% of their body weight), whereas untreated people gained an average of 6 kg. Corresponding body mass index (BMI) decreased by an average of 7.6 points in testosterone injection users, compared with a 2 point increase in the control group.
The waist circumference decreased by an average of 13 cm for those injecting hormones, compared with an increase of 7 cm in the control group. At the end of the study period, the people who were given testosterone injections had less visceral fat, less risk of cardiovascular disease.
Commenting on the results, Mr. Saad, a professor of medicine at Bayer, said: "Prolonged testosterone therapy in men with hypogonadism helps to lose weight effectively, contributing to reducing mortality and other variables. cardio ".
The researchers also presented specific data on men who were eligible for weight loss surgery. This is a treatment for obesity, including laparotomy, and gastric bypass. Weight-loss surgery is an effective method, but there are serious risks associated with surgery, which may not always yield positive results.
This study includes 76 men, with type 3 obesity (BMI of 40 or more), who are eligible for weight loss surgery. Of these, 59 were treated with testosterone and lost an average of 30 kg.
According to Saad, the results suggest testosterone therapy could be as effective as weight loss surgery, without the risk of serious complications. "We believe that testosterone therapy should be discussed with the patient as an alternative to surgery. Therapy should also be considered for non-surgical male patients," Saad said.